Drug Addiction

There are no specific treatments for drug use and substance use disorder (SUD). But inpatient and/or behavioral treatments may be helpful for people with a variety of substance use disorders. People who use psychedelics may experience one or several of a range of side effects, which range from moderate to severe. The effects of mescaline […]

Effect of kappa-opioid receptor agonists U69593, U50488H, spiradoline and salvinorin A on cocaine-induced drug-seeking in rats. Since Salvinorin A inhibits dopamine release, it also has little potential for addiction. Smoking is quicker and more efficient but may lead to discomfort in the chest. It can also be difficult to accurately gauge the dose when using […]

The psychedelic drug can cause visual hallucinations and change a person’s mood, emotions and perception. Because it has a high potential for abuse and no accepted medical use, LSD is illegal in the United States. However, despite being a Schedule 1 substance, there has been a resurgence of interest in potential therapeutic uses for LSD, […]

Interestingly, Potter and colleagues found that the average depression level (as measured by the Beck Depression Inventory) was 13.35 in people who used MDMA, 7 points higher than that of non-drug users (2013). Although this difference was not large enough to be significant, it is still important to note since MDMA users commonly report low […]

Researchers are also investigating other drugs sometimes classified as psychedelic and dissociative drugs, such as MDMA, and the way they work in the brain. Much of the research about the addictiveness of hallucinogens is conflicting. Some outlets report that dependence is the same as addiction, but a person can be dependent on a drug and not display any […]

Strassman and Qualls [87] found dose-dependent elevations in HR and BP with IV DMT. They found a larger and more rapid increase than with oral ingestion, reporting that a 0.4 mg/kg IV dose raised HR by approximately 26 BPM at 2 minutes, as well as SBP by 35 mmHg and DBP by 30 mmHg. In […]